Zusammenfassung
Myxoide Leiomyomata stellen eine seltene Variante uteriner Leiomyome dar. Sie sind
durch eine myxoide Beschaffenheit, fehlende mitotische Aktivität und einen myogenen
Phänotyp charakterisiert. Im vorliegenden Fall einer 38-jährigen Patientin zeigte
sich eine zystische Lymphangiom-ähnliche Komponente, die von endothelartigen Zellen
mit positiver CD 34-, CD 31- und Faktor VIII-Immunreaktivität ausgekleidet waren.
Aufgrund des fehlenden invasiven Wachstums konnte ein myxoides Leiomyosarkom als wichtigste
Differenzialdiagnose ausgeschlossen werden.
Summary
Myxoid leiomyomas of the uterus are uncommon. They are characterised by a myxoid stroma,
no mitotic activity and a myogenic phenotype. We present a case with focal lymphangioma-like
pattern. The solid compartiment showed positive immunoreactivity with muscular markers
and but no CD 34-immunostaining. Contrary, the endothelial-like cells of the cystic
part were positive with antibodies against CD 34, CD 31 and factor VIII, indicating
vascular differentiation. The lack of infiltrative growth patterns excluded myxoid
leiomyosarcoma as the major differenzial diagnosis.
Schlüsselwörter
Myom - Uterus - Leiomyosarkom - myxoid - Lymphangiom
Key words
Myoma - lymphangioma - leiomyosarcoma - degeneration - myxoid
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PD Dr. Lars-Christian Horn
Institut für Pathologie
Universität Leipzig
Liebigstraße 26
D-04103 Leipzig
Phone: +49 341-97 150 46
Fax: +49 341-97 150 39
Email: hornl@medizin.uni-leipzig.de
